We are located at the University of Ljubljana, Faculty of Chemistry and Chemical Technology.

We investigate the molecular basis of life with focus on the structure, function and evolution of proteins and their regulation by small molecules and macromolecules using a combination of experimental and computational methods.


MAIN RESEARCH TOPICS

Molecular mechanisms of allosteric regulation and oligomerization in papain-like cysteine peptidases.


Identification and characterization of novel protein/small molecule interactions with focus on the discovery of novel antibiotics and anti-cancer drugs.


GROUP NEWS

06-11-2019
Mateja successfully defended her PhD thesis. Congratulations and all the best at your new job!

10-2019
Mateja’s paper “Interplay between tetrameric structure, enzymatic activity and allosteric regulation of human dipeptidyl-peptidase I” was just accepted for publication in Archives of Biochemistry and Biophysics. The online version is available here.

05-2019
Mateja’s paper “The catalytic domain of cathepsin C (dipeptidyl-peptidase I) alone is a fully functional endoprotease” will appear in press. Congratulations!
The online version is available here.

04-2019
Group website launched!

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